Fig. 4 | Scientific Reports

Fig. 4

From: Investigating the binding potential of the Melissa officinalis oil against Alzheimer’s targets by molecular docking and in vitro evaluations

Fig. 4

2D and 3D view of the best docked ligands against Alzheimer’s disease targets; a: amyloid-β interaction with 3′,4′,5,7-tetrahydroxyflavone, 3′-O-β-D-glucuronopyranoside, γ-O-β-D-glucopyranoside, b: β-Secretase interaction with 2,3,19,23-tetrahydroxy-12-orsen-28-oic acid-23-sulfate, 28-O-β-D-glucopyranosyl ester; & c, d, e: γ-Secretase, acetylcholinesterase and neprilysin interaction with sagerinic acid, respectively. This figure was generated using Schrodinger’s Maestro molecular modeling software (version 2022.4).

Back to article page