Table 1 Clinical and biochemical characteristics of the participants.
The BUFF cohort (n = 156) | The SIMPLE cohort (n = 145) | The Combined cohort (n = 301) | |||||||
|---|---|---|---|---|---|---|---|---|---|
Transudate (n = 34) | Exudate (n = 122) | p | Transudate (n = 25) | Exudate (n = 120) | p | Transudate (n = 59) | Exudate(n = 242) | p | |
Age, years | 78 (69–83) | 65 (54–75) | < 0.001 | 78 (65–84) | 72 (65–78) | 0.122 | 78 (68–83) | 69 (60–77) | < 0.001 |
Sex, n (%) | 0.068 | 0.385 | 0.873 | ||||||
Female | 7 (21) | 40 (33) | 11 (44) | 39 (32) | 18 (31) | 79 (33) | |||
Male | 27 (79) | 82 (67) | 14 (56) | 81 (68) | 41 (69) | 163 (67) | |||
Pleural fluid LDH, U/L | 112 (77–151) | 370 (174–820) | < 0.001 | 84 (62–103) | 246 (168–464) | < 0.001 | 93 (68–137) | 318 (171–649) | < 0.001 |
Pleural fluid protein, g/L | 13 (10–18) | 28 (20–42) | < 0.001 | 15 (10–20) | 37 (28–43) | < 0.001 | 14 (10–20) | 34 (23–42) | < 0.001 |
Pleural fluid cholesterol, mmol/L | 0.68 (0.43–0.79) | 1.76 (1.11–2.25) | < 0.001 | 0.53 (0.41–0.81) | 1.69 (1.21–2.23) | < 0.001 | 0.67 (0.43–0.80) | 1.76 (1.15–2.24) | < 0.001 |
Serum LDH, U/L | 242 (192–293) | 201 (174–240) | 0.012 | 240 (208–277) | 207 (175–240) | 0.003 | 241 (205–292) | 204 (175–241) | < 0.001 |
Serum protein, g/L | 60 (56–65) | 65 (60–70) | 0.003 | 56 (52–62) | 61 (56–66) | 0.022 | 59 (54–63) | 63 (58–79) | < 0.001 |
Etiologies | CHF: 31 HP: 3 | PPE: 45 MPE: 35 TPE: 42 | CHF: 23 HP: 1 LC: 1 | PPE: 29 MPE:62 TPE: 19 PE: 4 Others: 6 | CHF: 54 HP: 4 LC:1 | PPE: 74 MPE:97 TPE: 61 PE: 4 Others: 6 | |||
