Table 1 Demographic information and clinical characteristics.
Variables | Control (n = 150) | SCOPD (n = 80) | AECOPD (n = 150) | P |
|---|---|---|---|---|
Age (years) | 75.54 ± 3.65 | 70.32 ± 1.21 | 73.84 ± 0.69 | 0.300 |
Male, n (%) | 99 (66.0) | 56 (70.0) | 112 (74.8) | 0.214 |
BMI | 22.35 ± 0.32 | 23.01 ± 0.14 | 22.65 ± 0.29 | 0.087 |
FEV1 (%) | N.A. | 1.14 (0.71, 1.52) | 0.94 (0.66, 1.35) | <0.01 |
FEV1/FVC (%) | N.A. | 69.25 (50.35, 94.56) | 53.34 (44.41, 71.51) | <0.01 |
FEV1 (L) | N.A. | 1.15 (0.75, 1.53) | 0.94 (0.66, 1.35) | <0.05 |
FVC (L) | N.A. | 2.22 (1.65, 2.65) | 1.90 (1.40, 2.33) | <0.05 |
Hospital stays (day) | N.A. | N.A. | 10 (8, 14) | N.A. |
CAT score | N.A. | N.A. | 26 (21, 30) | N.A. |
mMRC score | N.A. | N.A. | 3 (2, 3) | N.A. |
CCQ score | N.A. | N.A. | 32 (27, 38) | N.A. |
CRP (mg/L) | 2.3 (0.6, 7.6) | 11.5 (3.5, 33.9) | 28.8 (8.2, 54.9) | <0.05 |
IL-6 (pg/mL) | 2.3 (0.9, 6.5) | 3.5 (0.8, 13.5) | 6.0 (2.1, 21.3) | 0.095 |
MCP-1 (pg/mL) | 22.6 (11.3, 42.3) | 54.5 (10.3, 98.5) | 103.1 (72.1, 126.9) | <0.01 |
TNF-α (pg/mL) | 18.9 (3.2, 33.8) | 35.5 (12.3, 87.9) | 64.4 (50.7, 109.2) | <0.01 |
