Table 1 Baseline characteristics of melanoma patients.
From: Development of a machine learning-based model for prognostic prediction in melanoma
Characteristics | Total (n = 4875) n (%) | Train set (n = 3,900) n (%) | Test set (n = 975) n (%) | χ2/t/Z | P value |
|---|---|---|---|---|---|
Age recodes | 13.42 ± 3.16 | 13.36 ± 3.20 | 13.67 ± 2.98 | 773.37 | 0.9952 |
Sex | 0.46 | 0.9252 | |||
Male | 3189 (65.43) | 2567 (65.84) | 622 (63.79) | ||
Female | 1685 (34.57) | 1332 (34.16) | 353 (36.21) | ||
Race | 23.34 | 0.6303 | |||
White | 4716 (96.76) | 3772 (96.74) | 944 (96.82) | ||
Black | 63 (1.29) | 46 (1.18) | 17 (1.74) | ||
AI/An | 16 (0.33) | 15 (0.38) | 1 (10.10) | ||
A/PI | 79 (1.62) | 66 (1.69) | 13 (1.33) | ||
Year of diagnosis | 2013 (2010–2015) | 2012 (2010–2015) | 2013 (2010–2015) | -2.47 | 0.0653 |
LDH pretreatment | 358.10 | 0.0000 | |||
Unknown | 4320 (88.63) | 3449 (88.46) | 871 (89.33) | ||
Normal or low | 257 (5.27) | 204 (5.23) | 53 (5.44) | ||
High | 2979 (6.09) | 246 (6.31) | 51 (5.23) | ||
Breslow thickness | 5483.55 | 0.0000 | |||
> 0.0 or ≤ 0.1 | 125 (2.56) | 109 (2.80) | 16 (1.64) | ||
≥ 9.8 | 258 (5.29) | 208 (5.33) | 50 (5.13) | ||
No mass/tumor | 1370 (28.11) | 1117 (28.65) | 253 (25.95) | ||
Unknown | 3121 (64.03) | 2465 (63.22) | 656 (67.28) | ||
Mitotic rate | 8101.14 | 0.0000 | |||
Mitoses absent | 90 (1.85) | 78 (2.00) | 12 (1.23) | ||
≥ 11 mitoses | 169 (3.47) | 133 (3.41) | 36 (3.69) | ||
Other | 13 (0.27) | 11 (0.28) | 2 (0.21) | ||
Unknown | 4553 (93.41) | 3637 (93.28) | 916 (93.95) | ||
< 1 mitosis | 33 (0.68) | 28 (0.72) | 5 (0.52) | ||
Not in chart | 16 (0.33) | 12 (0.31) | 4 (0.41) | ||
CS lymph nodes | 731.67 ± 382.02 | 746.69 ± 374.50 | 671.52 ± 405.42 | 5.63 | 0.0000 |
Ulceration | 778.36 | 0.0000 | |||
Ulceration present | 316 (6.48) | 256 (6.57) | 60 (6.15) | ||
Not identified | 911 (18.69) | 742 (19.03) | 169 (17.33) | ||
Not assessed | 3647 (74.83) | 2901 (74.40) | 746 (76.51) | ||
Marital status | 125.66 | 0.0002 | |||
Widowed | 559 (11.47) | 451 (11.57) | 108 (11.08) | ||
Unmarried | 17 (0.35) | 15 (0.38) | 2 (0.21) | ||
Single | 956 (19.61) | 751 (19.26) | 205 (21.03) | ||
Separated | 51 (1.05) | 39 (1.00) | 12 (1.23) | ||
Married | 2814 (57.73) | 2261 (57.99) | 553 (56.72) | ||
Divorced | 477 (9.79) | 382 (9.80) | 95 (9.74) | ||
Median household income | 0.00 | 1.0000 | |||
Median (range) | 72499.5 (36,000.0–132,000.0) | 72,499.5 (36,000.0–132,000.0) | 72,499.5 (36,000.0–132,000.0) | ||
Sites recode | 0.00 | 1.0000 | |||
Skin | 4874 (100.00) | 3899 (100.00) | 975 (100.00) | ||
Primary site | 164.52 | 0.0000 | |||
C44.3-Skin | 270 (5.54) | 220 (5.64) | 50 (5.13) | ||
C44.4-Skin | 265 (5.44) | 202 (5.18) | 63 (6.46) | ||
C44.5-Skin | 620 (12.72) | 479 (12.29) | 141 (14.46) | ||
C44.6-Skin | 448 (9.19) | 373 (9.57) | 75 (7.69) | ||
C44.7-Skin | 447 (9.17) | 357 (9.16) | 90 (9.23) | ||
C44.9-Skin | 2824 (57.94) | 2268 (58.17) | 556 (57.03) |
