Fig. 5
From: Bioinformatics analysis of immune-related differentially expressed genes in Kawasaki disease
GO and KEGG Enrichment Analysis for IMRDEGs. (A) bar chart of gene ontology (GO) and pathway (KEGG) enrichment analysis results of immunomodulatory differentially expressed genes (IMRDEGs) (B) Bubble plot of gene ontology (GO) and pathway (KEGG) enrichment analysis results of immunomodulation-related differentially expressed genes (IMRDEGs). The ordinate is the GO terms and KEGG terms. (C–F) Gene ontology (GO) and pathway (KEGG) enrichment analysis results of immunomodulatory differentially expressed genes (IMRDEGs): BP (C), CC (D), MF (E) and KEGG (F). The orange nodes represent items, the green nodes represent molecules, and the lines represent the relationship between items and molecules. IMRDEGs, Immunomodulatory-Related Differentially Expressed Genes; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; BP, Biological Process; CC, Cellular Component; MF, Molecular Function. The bubble size in the bubble plot represents the number of genes, and the color of the bubble represents the size of the adj. P-value, the reder the color, the smaller the adj. P-value, and the bluer the color, the larger the adj. P-value. The screening criteria for gene ontology (GO) and pathway (KEGG) enrichment analysis were P. adj < 0.05 and FDR value (q value) < 0.05, and the p value correction method was Benjamini-Hochberg (BH).
