Table 6 Multivariable binary logistic regression analysis of factors associated with severe symptoms of BPH at Dessie comprehensive specialized Hospital, 2024 (n = 232).

From: Predictors and predictive performance of immune–inflammation indices for symptom severity in benign prostatic hyperplasia

Variables

BPH symptom severity

AOR (95% CI)

P- value

Mild-moderate (N = 148)

Sever (N = 84)

Age categories

40–64

86 (58.1%)

28(33.3%)

1

-

 65

62 (41.9%)

56 (66.7%)

2.55 (1.19 5.45)

0.016*

Residence

Urban

55 (37.2%)

20(23.8%)

1

-

Rural

93 (62.8%)

64 (76.2%)

1.17 (0.53, 2.57)

0.700

Physical activity

Low

57 (38.5%)

51 (60.7%)

2.56 (1.22, 5.35)

0.013*

Adequate

91 (61.5%)

33 (39.3%)

1.00

-

Number of servings of FEV intakes

< 5 servings

102 (68.9%)

65 (77.4%)

0.91 (0.37, 2.23)

0.836

≥ 5 servings

46 (31.1%)

19 (22.6%)

1

-

Khat chewing

Non-chewer

100 (67.6%)

50 (59.5%)

1

-

Khat chewer

48 (32.4%)

34 (40.5%)

2.05 (0.92, 4.57)

0.078

BPH duration

-

-

-

1.03 (0.86,1.23)

0.732

Prostate Size

-

-

-

0.99 (0.98, 1.01)

0.510

BMI

Underweight

7 (4.7%)

8 (9.5%)

3.49 (14.00)

0.078

Normal weight

134 (90.5%)

72 (85.7%)

1

-

Overweight/obese

7 (4.7%)

4 (4.8%)

0.41 (2.19)

0.296

Central obesity

No

129(87.2%)

57 (67.9%)

1

-

Yes

19 (12.8%)

27 (32.1%)

2.79 (1.07, 7.25)

0.035*

Diabetes

No

129 (87.2%)

67 (79.8%)

1

-

Yes

19 (12.8%)

17 (20.2%)

1.12 (0.43, 2.94)

0.820

Hypertension

< 140

112 (75.7%)

57 (67.9%)

1

-

>=140

36 (24.3%)

27 (32.1%)

1.42 (0.60, 3.37)

0.430

SII value

< 564.92 × 103

108 (73.0%)

23 (27.4%)

1

-

>=564.92 × 103

40 (27.0%)

61 (72.6%)

2.97 (1.10, 7.98)

0.031*

PII value

< 273.3 × 106

107(72.3%)

23(27.4%)

1

-

>=273.3 × 106

41(27.7%)

61 (72.6%)

2.46 (1.04, 5.86)

0.042*

NLR value

< 1.368

73 (49.3%)

8 (9.5%)

1

-

>= 1.368

75 (50.7%)

76 (90.5%)

2.87 (1.01, 8.14)

0.048*

PLR value

< 143.791

97 (65.5%)

97 (65.5%)

27 (32.1%)

-

>= 143.791

51 (34.5%)

51 (34.5%)

57 (67.9%)

0.388

  1. AOR Adjusted odds ratio, FEV Fruit and vegetable intake, SII Systemic immune-inflammation index, PII Pan immuno-inflammatory index, NLR Neutrophil-lymphocyte ratio, PLR Platelet to lymphocyte ratio.
  2.  The bold values *  indicate statistically significant results (p-value < 0.05).