Table 2 Neurological assessment of pediatric patients.

From: Impact of meningoencephalitis and sepsis on delirium and subsequent neurological impairment in pediatric patients: a prospective proof-of-concept biomarker and EEG study

 

Patients

Controls

p value

Meningoencephalitis

Sepsis

p value

Delirium

No delirium

p value

Abnormal EEG

Normal EEG

p value

Number (n)

24

11

 

9

15

 

12

12

 

8

16

 

FSS day 1

9.0 [7.0,10.2]

6.0 [6.0,6.5]

< 0.001

7.0 [7.0,9.0]

10.0 [8.5,11.5]

0.019

10.0 [9.8,12.0]

7.5 [7.0,9.0]

0.009

9.0 [7.8,12.0]

9.5 [7.0,10.0]

0.577

FSS day 3

7.0 [6.8,7.2]

NA

NA

7.0 [6.0,7.0]

7.0 [7.0,9.0]

0.198

7.0 [7.0,9.0]

7.0 [6.0,7.0]

0.120

7.0 [7.0,9.5]

7.0 [6.0,7.0]

0.176

FSS day 5

6.0 [6.0,7.0]

NA

NA

7.0 [6.0,7.0]

6.0 [6.0,7.0]

0.697

6.0 [6.0,7.2]

6.5 [6.0,7.0]

1.0

7.0 [6.0,7.2]

6.0 [6.0,7.0]

0.242

GCS day 1

15.0 [13.8,15.0]

15.0 [15.0,15.0]

0.009

15.0 [15.0,15.0]

14.0 [13.0,15.0]

0.042

13.5 [13.0,14.0]

15.0 [15.0,15.0]

< 0.001

14.5 [12.8,15.0]

15.0 [14.0,15.0]

0.459

GCS day 3

15.0 [15.0,15.0]

NA

NA

15.0 [15.0,15.0]

15.0 [15.0,15.0]

0.804

15.0 [15.0,15.0]

15.0 [15.0,15.0]

0.166

15.0 [15.0,15.0]

15.0 [15.0,15.0]

0.610

GCS day 5

15.0 [15.0,15.0]

NA

NA

15.0 [15.0,15.0]

15.0 [15.0,15.0]

0.621

15.0 [15.0,15.0]

15.0 [15.0,15.0]

0.209

15.0 [15.0,15.0]

15.0 [15.0,15.0]

0.732

RASS day 1

0.0 [-1.0,0.0]

0.0 [0.0,0.0]

0.266

0.0 [0.0,0.0]

0.0 [-1.0,0.5]

0.799

-1.0 [-1.0,0.2]

0.0 [0.0,0.0]

0.096

0.0 [-1.2,0.2]

0.0 [-1.0,0.0]

0.870

RASS day 3

0.0 [0.0,0.0]

NA

NA

0.0 [0.0,0.0]

0.0 [0.0,0.0]

0.710

0.0 [-1.0,0.0]

0.0 [0.0,0.0]

0.264

0.0 [0.0,0.0]

0.0 [0.0,0.0]

0.566

RASS day 5

0.0 [0.0,0.0]

NA

NA

0.0 [0.0,0.0]

0.0 [0.0,0.0]

0.442

0.0 [0.0,0.0]

0.0 [0.0,0.0]

0.619

0.0 [0.0,0.0]

0.0 [0.0,0.0]

0.492

POPC day 90

1.0 [1.0,1.0]

NA

NA

1.0 [1.0,1.0]

1.0 [1.0,1.0]

0.756

1.0 [1.0,1.0]

1.0 [1.0,1.0]

1.0

1.0 [1.0,1.0]

1.0 [1.0,1.0]

0.655

PCPC day 90

1.0 [1.0,1.0]

NA

NA

1.0 [1.0,1.0]

1.0 [1.0,1.0]

NA

1.0 [1.0,1.0]

1.0 [1.0,1.0]

NA

1.0 [1.0,1.0]

1.0 [1.0,1.0]

NA

FSS day 90

6.0 [6.0,6.0]

NA

NA

6.0 [6.0,6.0]

6.0 [6.0,6.0]

NA

6.0 [6.0,6.0]

6.0 [6.0,6.0]

NA

6.0 [6.0,6.0]

6.0 [6.0,6.0]

NA

RASS day 90

0.0 [0.0,0.0]

NA

NA

0.0 [0.0,0.0]

0.0 [0.0,0.0]

NA

0.0 [0.0,0.0]

0.0 [0.0,0.0]

NA

0.0 [0.0,0.0]

0.0 [0.0,0.0]

NA

GCS day 90

15.0 [15.0,15.0]

NA

NA

15.0 [15.0,15.0]

15.0 [15.0,15.0]

1.0

15.0 [15.0,15.0]

15.0 [15.0,15.0]

1.0

15.0 [15.0, 15.0]

15.0 [15.0,15.0]

NA

  1. FSS = Functional status scale; GCS = Glasgow coma score; NA = Not accessible; PCPC = Pediatric cerebral performance scale; POPC = Pediatric overall performance scale; RASS = Richmond agitation and sedation scale. Values are given as medians [interquartile range].
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