Table 2 The association between eGDR groups and mortality.

From: Low estimated glucose disposal rate (eGDR) predicts decreased all-cause mortality in critically ill patients with cardiorenal syndrome (CRS): analysis of the MIMIC-IV database

 

Model 1

Model 2

Model 3

HR (95%CI)

P-value

HR (95%CI)

P-value

HR (95%CI)

P-value

Categories

      

Follow-up in 30 days

      

eGDR as continuous

1.11(1.06,1.16)

 < 0.001

1.08(0.99,1.17)

0.059

1.12(1.03,1.22)

0.004

Quartile

      

Q1

Ref

 

Ref

 

Ref

 

Q2

1.01(0.71,1.41)

0.963

0.81(0.55,1.17)

0.264

1.04(0.71,1.50)

0.846

Q3

1.45(1.06,1.98)

0.020

1.06(0.72,1.56)

0.771

1.43(0.97,2.11)

0.066

Q4

1.80(1.33,2.43)

 < 0.001

1.26(0.82,1.92)

0.285

1.73(1.14,2.61)

0.008

P for trend

 

 < 0.001

 

0.164

 

0.003

Follow-up in 90 days

      

eGDR as continuous

0.99(0.996,1.01)

0.218

1.06(0.98,1.13)

0.096

1.09(1.02,1.17)

0.012

Quartile

      

Q1

Ref

 

Ref

 

Ref

 

Q2

1.08(0.82,1.43)

0.584

0.98(0.73,1.29)

0.876

1.12(0.85,1.49)

0.438

Q3

1.46(1.12,1.89)

0.004

1.26(0.96,1.65)

0.093

1.47(1.12,1.93)

0.005

Q4

1.89(1.47,2.43)

 < 0.001

1.73(1.34,2.24)

 < 0.001

1.91(1.46,2.48)

 < 0.001

P for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

Follow-up in 180 days

      

eGDR as continuous

0.99(0.99,1.01)

0.238

1.11(1.01,1.21)

0.025

1.08(1.02,1.15)

0.011

Quartile

      

Q1

Ref

 

Ref

 

Ref

 

Q2

1.09(0.84,1.40)

0.514

0.99(0.76,1.27)

0.933

1.11(0.85,1.43)

0.425

Q3

1.49(1.17,1.89)

0.001

1.29(1.01,1.65)

0.039

1.47(1.15,1.89)

0.002

Q4

1.85(1.47,2.33)

 < 0.001

1.69(1.28,2.06)

 < 0.001

1.84(1.44,2.34)

 < 0.001

P for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

Follow-up in 360 days

      

eGDR as continuous

0.99(0.99,1.01)

0.246

1.04(0.97,1.09)

0.217

1.06(0.99,1.12)

0.052

Quartile

      

Q1

Ref

 

Ref

 

Ref

 

Q2

1.06(0.85,1.32)

0.616

0.96(0.77,1.21)

0.762

1.07(0.85,1.34)

0.549

Q3

1.360(1.103,1.677)

0.004

1.19(0.96,1.47)

0.113

1.33(1.07,1.65)

0.010

Q4

1.67(1.36,2.04)

 < 0.001

1.48(1.20,1.82)

 < 0.001

1.64(1.32,2.03)

 < 0.001

P for trend

 

 < 0.001

 

 < 0.001

 

 < 0.001

  1. Model 1 was unadjusted. Model 2 was adjusted by Age, Gender, BMI. Model 3 was adjusted for Age, Gender, BMI, Glucose, PLT, PT, INR, CVD, CRRT, TnT, PTT.
  2. BMI body mass index; RBC red blood cell; WBC white blood cell; PLT platelet; HbA1C glycosylated hemoglobin; AST aspartate transaminase; PT prothrombin time; PTT partial thromboplastin time; INR international normalized ratio; CK-MB creatine kinase MB isoenzyme; TnT Troponin T; CVD cerebrovascular disease; CRRT continuous renal replacement therapy; HR hazard ratio; CI confidence interval.
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