Fig. 8 | Scientific Reports

Fig. 8

From: Pyridoxamine inhibits dopamine-induced α-synuclein oligomerization through scavenging neurotoxic dopamine quinone

Fig. 8

(A) SDS-PAGE analysis of α-Syn treated with DA (0–100 molar eq. to α-Syn). Relative oxidation (%) of (B) M1DVFM5KGLSKAKE, (C) DM116PVDPDNE, and (D) AYEM127PSEE in monomer (M), dimer (D), and oligomer (O) bands of SDS-PAGE (DA, 1–100 molar equation) in (A). Each band was cut out and subjected to in-gel digestion with V8. The peptides were analyzed by LC/ESI-MS and MS/MS. Results are presented as the mean ± SEM (error bars) from triplicate experiments.

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