Fig. 2
From: Systemic downregulation of EV-associated MiRNAs following remote ischemic preconditioning
Global miRNA Profile Changes Following RIPC. (A) Principal Component Analysis of the 134 miRNA profiles. Each point represents a sample, with lines connecting the pre- and post-RIPC samples for each patient. The plot shows a consistent directional shift post-intervention. (B) Volcano plot illustrating the log2 fold change and statistical significance (-log10 p-value) for each miRNA. The four significantly downregulated miRNAs (p < 0.05) are highlighted in red.
