Fig. 5 | Scientific Reports

Fig. 5

From: Systemic downregulation of EV-associated MiRNAs following remote ischemic preconditioning

Fig. 5

Predicted miRNA-Gene-Pathway Interaction Network. The network visualizes the connections between significantly downregulated miRNAs (p < 0.05, blue nodes), their validated gene targets that are part of a leading-edge subset (grey nodes), and the significantly enriched Hallmark pathways (FDR < 0.2, green nodes). The layout highlights the central role of the downregulated miRNAs in regulating a large number of genes across multiple protective pathways.

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