Fig. 3

Evaluation of metaphase cell selection efficiency with and without centromere staining by two independent scorers. (A) Inter-scorer variation in identifying metaphase cells from centromere-stained images. (B) Inter-scorer variation in identifying metaphase cells from unstained images. Statistical significance assessed by Z-score. (C) Comparison of the average (%) of rejected cells between centromere-stained and unstained metaphase cells across the three scorers. (D) Representative images of metaphase cells with and without centromere probe staining.