Table 1 Characteristics of the studies related to TPT acceptance in Chinese children and adolescents.
Study | Study design | Region | Study year | Research setting | Preventive therapy criteria | Regimen | Sample size | Initiated TPT |
|---|---|---|---|---|---|---|---|---|
Dong et al.31 | Cross-sectional study | Jiangsu Province | 2005 | Routine screening | TST ≥ 20 mm or strong reaction (blisters, necrosis, lymphangitis) | 6H2P2 | 307 | 260 |
Guo et al.32 | Cross-sectional study | Jiangsu Province | 2018–2021 | Routine screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) or IGRA positive | 3HR | 397 | 215 |
Zhou et al.35 | Cross-sectional study | Guangdong Province | 2011 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 6 H | 187 | 150 |
Wu33 | Cross-sectional study | Chongqing Municipality | 2017–2018 | Household contact screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3H2P2 | 25 | 20 |
Wu33 | Cross-sectional study | Chongqing Municipality | 2017–2018 | Household contact screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 6 H | 26 | 19 |
Shi34 | Cross-sectional study | Sichuan Province | 2016 | Routine screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 31 | 3 |
Yu et al.36 | Cross-sectional study | Henan Province | 2010 | Routine screening | TST ≥ 10 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 846 | 627 |
Hu et al.37 | Cross-sectional study | Henan Province | 2017 | Routine screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 397 | 248 |
Guan et al.38 | Cross-sectional study | Shandong Province | Not reported | Routine screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3H2P2 | 24 | 16 |
Jiang et al.39 | Cross-sectional study | Shandong Province | Not reported | Routine screening | TST ≥ 20 mm or strong reaction (blisters, necrosis, lymphangitis) | 3H2P2 | 26 | 16 |
Pan et al.40 | Cross-sectional study | Guangxi Province | 2019–2020 | Routine screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 90 | 10 |
Jia et al.41 | Cross-sectional study | Beijing Municipality | 2018–2019 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3H2P2 | 62 | 39 |
Weng et al.42 | Cross-sectional study | Zhejiang Province | 2013–2014 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 23 | 21 |
Li et al.43 | Cross-sectional study | Henan Province | 2018 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3H2P2 | 143 | 111 |
Zheng44 | Cross-sectional study | Liaoning Province | 2015 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 6 H | 64 | 42 |
Gong et al.45 | Cross-sectional study | Zhejiang Province | 2016 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 11 | 10 |
Hou et al.46 | Cross-sectional study | Guangxi Province | 2023 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 100 | 31 |
Wang et al.47 | Cross-sectional study | Shanxi Province | Not reported | Routine screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 6 H | 63 | 38 |
Fan et al.48 | Cross-sectional study | Chongqing Municipality | 2020–2021 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) or IGRA positive | 3HR | 44 | 36 |
Chen et al.49 | Cross-sectional study | Henan and Hunan Province | 2018–2020 | Household contact screening | IGRA positive | 6 H | 228 | 185 |
Chen et al.49 | Cross-sectional study | Henan and Hunan Province | 2018–2020 | Household contact screening | IGRA positive | 3H2P2 | 273 | 234 |
Chen et al.49 | Cross-sectional study | Chongqing Municipality | 2018–2020 | Household contact screening | IGRA positive | 6 H | 149 | 120 |
Chen et al.49 | Cross-sectional study | Chongqing Municipality | 2018–2020 | Household contact screening | IGRA positive | 3H2P2 | 39 | 25 |
Li et al.50 | Cohort study | Jiangsu Province | 2004–2007 | Routine screening | TST ≥ 20 mm or strong reaction (blisters, necrosis, lymphangitis) | 6 H | 195 | 92 |
Li et al.51 | Cohort study | Beijing Municipality | 2016–2019 | School outbreak screening | TST ≥ 10 mm or strong reaction (blisters, necrosis, lymphangitis) | 3H2P2 | 91 | 72 |
Fang et al.52 | Cohort study | Zhejiang Province | 2016–2019 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 6 H | 30 | 4 |
Fang et al.53 | Cohort study | Zhejiang Province | 2019 − 2010 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 6 H | 122 | 69 |
Huang54 | Cohort study | Guangdong Province | 2013–2017 | Routine screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 348 | 151 |
Zou et al.55 | Cohort study | Hunan Province | 2020–2021 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 144 | 130 |
Hu et al.56 | Cohort study | Shanghai Municipality | 2018–2020 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3H2P2 | 12 | 5 |
Zhou et al.57 | Cohort study | Henan Province | 2019–2021 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 136 | 110 |
Weng et al.58 | Cohort study | Zhejiang Province | 2008–2012 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 179 | 86 |
Tang et al.59 | Cohort study | Anhui Province | 2018–2019 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 52 | 34 |
Zhang et al.60 | Cohort study | Jiangsu Province | 2014–2016 | School outbreak screening | TST ≥ 10 mm or strong reaction (blisters, necrosis, lymphangitis) | 3HR | 34 | 4 |
Xu et al.61 | Cohort study | Zhejiang Province | 2018–2020 | School outbreak screening | TST ≥ 15 mm or strong reaction (blisters, necrosis, lymphangitis) | 3H2P2 | 31 | 30 |