Table 3 Bivariable analysis of risk factors for early mortality among preterm neonates with RDS admitted at HRRH.

From: Clinical–radiological profile and risk factors for early mortality in preterm neonates with respiratory distress syndrome in Hoima, Western Uganda

Characteristic

Survived, N = 121

Died, N = 29

Bivariable analysis

cRR

95% CI

P value

Age at admission (hrs)

≤ 6 h

111(91.7)

10(34.5)

Ref

  

> 6 h

10(8.3)

19(65.5)

1.773

1.481–2.122

< 0.001

Sex

Male

73(60.3)

21(72.4)

1.084

0.957–1.228

0.205

Female

48(39.7)

8(27.6)

Ref

  

DM in pregnancy

No

101(83.5)

27(93.1)

Ref

  

Yes

20(16.5)

2(6.9)

0.887

0.772–1.020

0.291

Infection in pregnancy

No

71(58.7)

19(65.5)

Ref

  

Yes

50(41.3)

10(34.5)

0.957

0.843–1.086

0.491

Prenatal steroids

No

55(45.5)

18(62.1)

1.109

0.978–1.258

0.107

Yes

66(54.5)

11(37.9)

Ref

  

Fever post delivery

No

94(77.7)

23(79.3)

Ref

  

Yes

27(22.3)

6(20.7)

0.985

0.848–1.145

0.847

Gestational age

< 32

86(71.1)

20(69.0)

0.984

0.855–1.133

0.825

32+

35(28.9)

9(31.0)

Ref

  

Birth weight

< 1.5

83(68.6)

28(96.6)

1.254

1.141–1.379

< 0.001

1.5+

38(31.4)

1(3.4)

Ref

  

APGAR

< 7

21(17.4)

5(17.2)

0.999

0.845–1.180

0.988

7+

100(82.6)

24(82.8)

Ref

  

Delivery mode

SVD

90(74.4)

25(86.2)

Ref

  

CS

31(25.6)

4(13.8)

0.902

0.792–1.027

0.119

Tachypnea

No

19(15.7)

4(13.8)

Ref

  

Yes

102(84.3)

25(86.2)

1.023

0.864–1.212

0.791

Recessions (intercostal/subcostal)

No

34(28.1)

9(31.0)

Ref

  

Yes

87(71.9)

20(69.0)

0.978

0.848–1.127

0.758

Grunting

No

55(45.5)

19(65.5)

Ref

  

Yes

66(54.5)

10(34.5)

0.882

0.778-1.000

0.250

Nasal flaring

No

63(52.1)

19(65.5)

Ref

  

Yes

58(47.9)

10(34.5)

0.919

0.812–1.040

0.282

Cyanosis

No

112(92.6)

24(82.8)

Ref

  

Yes

9(7.4)

5(17.2)

1.198

0.925–1.552

0.172

Radiology patterns

Ground glass pattern

55(45.5)

10(34.5)

Ref

  

Reticulo-nodular opacity

35(28.9)

10(34.5)

1.071

0.922–1.244

0.371

Fine reticulo-nodular

22(18.2)

8(27.6)

1.119

0.934–1.341

0.222

Fine reticular

9(7.4)

1(3.4)

0.948

0.771–1.164

0.608

  1. cRR = Crude rate ratio, CI = Confidence interval, SVD = spontaneous vaginal delivery, CS = Cesarean section.