Fig. 2 | Scientific Reports

Fig. 2

From: Identification of competing endogenous RNA networks involved in phrenic nerve stimulation preventing mechanical ventilation induced diaphragm dysfunction

Fig. 2

Identification of DE mRNAs, DE circRNAs and DE miRNAs. Study design flowchart (A). Principal component analysis (PCA) score plot showing sample grouping (B). Volcano plots presenting the differentially expressed miRNAs (C, D), circRNA (F, G) and mRNAs (I, J) between MV vs Control group and PNS vs MV group. The horizontal dashed line indicates the threshold for significance (P ≤ 0.05) and the vertical dashed line indicates the up-regulated (right side) and down-regulated (left side) RNAs. Up-regulated miRNAs were marked in red and down-regulated miRNAs are indicated in blue. Venn cluster of the DE miRNAs (E), DE circRNA (H) and DE mRNAs (K) in MV vs Control group and PNS vs MV group, with the orange section representing MV vs Control group and the blue representing PNS vs MV. C: control group, M: MV group, P: PNS group. The same as below.

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