Table 2 Distribution of genetic alterations across molecular groups.

From: An integrated approach to molecular profiling supports precision diagnosis of pediatric medulloblastoma in Argentina amid the resource-constrained setting

Altered marker

WNT

(n = 9)

SHH TP53- (n = 13)

SHH TP53+ (n = 10)

Non-WNT/non-SHH (n = 51)

NOS (n = 1)

GAB1

1/9

8/13

8/10

2/51

0/1

YAP1

4/9

10/13

8/10

2/51

0/1

CTNNB1 (β-Catenin)

4/9

0/13

0/10

0/51

0/1

TP53 (P53)

2/9

0/13

10/10

12/51

0/1

Mon Chr. 6

5/9

0/13

0/10

0/51

0/1

i17q

0/9

0/13

0/10

11/51

0/1

MYCN

0/9

0/13

3/10

15/51

0/1

MYC

1 /9

0/13

0/10

7/51

0/1

  1. Mon Chr. 6: Chromosome 6 monosomy.
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