Fig. 3 | Scientific Reports

Fig. 3

From: Anthracyclines effect on mitochondrial function and biogenesis in normal blood cells of hodgkin lymphoma patients

Fig. 3

Metabolic and mitochondrial genetic characteristics of peripheral blood mononuclear cells in patients with Hodgkin lymphoma. Baseline, interim, and end of therapy (EoT) metabolic and mitochondrial genetic characteristics of peripheral blood mononuclear cells in responder (blue) and non-responder (red) patients with Hodgkin lymphoma. (A) Glycolytic flux. (B) Overall oxygen consumption rate (OCR). (C) ATP-linked, (D) ATP-independent, and (E) extra-mitochondrial OCR. (F) Monocyte/lymphocyte ratio. Mitochondrial DNA copy number (mtDNA-CN) in (G) responder and (H) non-responder patients. *p < 0.05; #p < 0.05 vs. corresponding baseline; ns: not significant.

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