Table 2 Association between LBMI and functional outcomes at 3 months.

From: Impact of lean body mass index on short-term outcomes in patients with ischemic stroke: an observational cohort study

 

Events, n (%)

Age and sex-adjusted

MV-adjusted

MV and FMI-adjusted*

OR

(95% CI)

P

OR

(95% CI)

P

OR

(95% CI)

P

Poor functional outcome

 Q1 (8.5–15.8), n = 2685

959 (35.7)

1.00

(reference)

 

1.00

(reference)

 

1.00

(reference)

 

 Q2 (12.4–16.9), n = 2683

611 (22.8)

0.63

(0.56–0.72)

 < 0.001

0.65

(0.56–0.75)

 < 0.001

0.66

(0.57–0.78)

 < 0.001

 Q3 (13.3–17.9), n = 2684

519 (19.3)

0.59

(0.52–0.67)

 < 0.001

0.63

(0.54–0.73)

 < 0.001

0.65

(0.55–0.78)

 < 0.001

 Q4 (14.2–29.2), n = 2683

469 (17.5)

0.65

(0.56–0.74)

 < 0.001

0.67

(0.57–0.79)

 < 0.001

0.72

(0.57–0.90)

0.004

Functional dependency

 Q1 (8.5–15.8), n = 2559

833 (32.6)

1.00

(reference)

 

1.00

(reference)

 

1.00

(reference)

 

 Q2 (12.4–16.9), n = 2636

564 (21.4)

0.67

(0.59–0.76)

 < 0.001

0.68

(0.58–0.79)

 < 0.001

0.69

(0.59–0.81)

 < 0.001

 Q3 (13.3–17.9), n = 2650

485 (18.3)

0.63

(0.55–0.72)

 < 0.001

0.67

(0.57–0.78)

 < 0.001

0.68

(0.57–0.82)

 < 0.001

 Q4 (14.2–29.2), n = 2653

439 (16.6)

0.70

(0.60–0.80)

 < 0.001

0.70

(0.60–0.83)

 < 0.001

0.73

(0.58–0.93)

0.009

  1. Poor functional outcome and functional dependency were defined as modified Rankin Scale scores of 3–6 and of 3–5 at 3 months after stroke onset, respectively. Lean body mass index was categorized into four groups according to quartiles by sex, respectively.
  2. Multivariable model included age, sex, hypertension, dyslipidemia, diabetes mellitus, smoking, drinking, atrial fibrillation, chronic kidney disease, history of stroke, stroke subtype (cardioembolism, small-vessel occlusion, large-artery atherosclerosis, or others), National Institutes of Health Stroke Scale score on admission, and reperfusion therapy.
  3. LBMI, lean body mass index; MV, multivariable; FMI, fat mass index; OR, odds ratio; CI, confidence interval.
  4. *Fat mass index was added to multivariable model.
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