Table 3 Death risk of extranodal marginal zone B-cell lymphoma: subgroup analysis by age (Model V).
From: Prognostic outcome of extranodal marginal zone B-cell lymphoma: a nationwide cohort
Age < 50 | P value | 50 ~ 59 | P value | 60 ~ 69 | P value | 70 ~ 79 | P value | |
|---|---|---|---|---|---|---|---|---|
HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |||||
Male sex | 1.20 (0.24–5.93) | 0.822 | 3.15 (1.26–7.85) | 0.014 | 1.87 (1.02–3.43) | 0.044 | 2.75 (1.67–4.53) | < .0001 |
SEER | ||||||||
Localized | 1 | 1 | 1 | 1 | ||||
Regional | 3.74 (0.74–18.85) | 0.110 | 0.87 (0.20–3.81) | 0.856 | 2.60 (1.32–5.15) | 0.006 | 1.83 (0.94–3.57) | 0.078 |
Metastatic | 3.18 (0.84–12.05) | 0.089 | 1.79 (0.67–4.79) | 0.245 | 1.88 (0.97–3.64) | 0.061 | 4.71 (2.89–7.68) | < .0001 |
Unknown | 0.48 (0.06–3.83) | 0.484 | 0.93 (0.35–2.43) | 0.879 | 1.98 (1.13–3.47) | 0.017 | 1.37 (0.78–2.40) | 0.270 |
Hypertension | 4.08 (1.15–14.45) | 0.029 | 1.53 (0.68–3.46) | 0.305 | 1.76 (1.00–3.08) | 0.050 | 0.82 (0.50–1.34) | 0.436 |
Diabetes mellitus | NA | 1.06 (0.44–2.55) | 0.902 | 0.86 (0.51–1.44) | 0.567 | 2.85 (1.74–4.66) | < .0001 | |
Heart disease | NA | 0.43 (0.06–3.24) | 0.414 | 1.74 (0.85–3.58) | 0.132 | 2.68 (1.66–4.32) | < .0001 | |
Cerebrovascular disease | NA | NA | 2.66 (1.32–5.38) | 0.006 | 1.58 (0.94–2.66) | 0.087 | ||
Income | ||||||||
< 20% | 1 | 1 | 1 | 1 | ||||
< 40% | 0.6 (0.12–2.91) | 0.525 | 0.78 (0.28–2.16) | 0.639 | 0.91 (0.49–1.69) | 0.761 | 1.09 (0.57–2.12) | 0.791 |
< 70% | 0.2 (0.04–1.08) | 0.061 | 0.81 (0.31–2.12) | 0.669 | 0.66 (0.36–1.20) | 0.175 | 0.80 (0.44–1.45) | 0.465 |
≥ 70% | 0.45 (0.1–1.99) | 0.289 | 0.52 (0.19–1.40) | 0.194 | 0.39 (0.20–0.75) | 0.005 | 0.69 (0.39–1.23) | 0.209 |
Unknown | NA | NA | 0.56 (0.07–4.21) | 0.571 | 0.39 (0.05–3.00) | 0.364 | ||
Moderate-intensity physical activity | ||||||||
0 day/week | 1 | 1 | 1 | 1 | ||||
1–2 day/week | 0.43 (0.11–1.62) | 0.210 | 0.70 (0.32–1.54) | 0.369 | 1.15 (0.67–1.98) | 0.613 | 0.54 (0.30–0.97) | 0.040 |
3–5 day/week | 0.28 (0.03–2.20) | 0.224 | 0.43 (0.15–1.25) | 0.120 | 0.51 (0.26–1.00) | 0.049 | 0.62 (0.35–1.10) | 0.099 |
6–7 day/week | NA | 0.995 | 0.78 (0.18–3.35) | 0.736 | 1.19 (0.52–2.71) | 0.674 | 0.53 (0.23–1.20) | 0.127 |
Body mass index | 0.96 (0.82–1.13) | 0.638 | 0.88 (0.78–1.00) | 0.042 | 1.03 (0.95–1.10) | 0.507 | 0.90 (0.84–0.98) | 0.009 |
Smoking status | ||||||||
Never | 1 | 1 | 1 | 1 | ||||
Past | 1.21 (0.10–13.97) | 0.880 | 1.19 (0.44–3.24) | 0.731 | 0.87 (0.45–1.67) | 0.669 | 0.79 (0.46–1.35) | 0.389 |
Current | 5.34 (1.04–27.39) | 0.045 | 1.19 (0.44–3.19) | 0.735 | 1.67 (0.81–3.43) | 0.161 | 0.91 (0.50–1.66) | 0.754 |
Drinking status | ||||||||
None | 1 | 1 | 1 | 1 | ||||
1/week | 0.22 (0.05–1.12) | 0.068 | 0.72 (0.29–1.76) | 0.469 | 0.53 (0.22–1.25) | 0.146 | 0.84 (0.36–1.99) | 0.699 |
2–3/week | 0.20 (0.03–1.15) | 0.071 | 0.18 (0.04–0.80) | 0.024 | 0.75 (0.38–1.49) | 0.412 | 1.04 (0.56–1.94) | 0.897 |
4–5/week | 0.56 (0.06–5.05) | 0.608 | 0.94 (0.26–3.41) | 0.922 | 0.31 (0.04–2.30) | 0.252 | 0.62 (0.18–2.07) | 0.432 |
≥ 6/week | NA | 0.997 | 0.96 (0.21–4.40) | 0.955 | 0.78 (0.23–2.62) | 0.690 | 0.64 (0.27–1.50) | 0.303 |
