Fig. 4 | Scientific Reports

Fig. 4

From: In vitro anti-inflammatory potential and in vivo anti-arthritis activities of Ximenia caffra extract on antigen-induced arthritis in rats

Fig. 4

Photomicrographs of muscles taken from control rats or those submitted to adjuvant-induced arthritis (AIA). In the control groups, the muscles exhibited normal morphology (A, a). In AIA group, the muscle showed signs of damage where asterisk: nuclear aggregations; blue arrow: inflammatory infiltrate (B, b). While induced animals were treated with 26, 50 and 100 mg/kg X. caffra seeds extract respectively showing normal muscle fibers (yellow arrows) (C–E) & (c–e). The last group where induced animals treated with MTX as standard drug showed slight necrosis in muscles (green arrow). Where (A–F) Staining: hematoxylin and eosin (20× magnification) while (a–f) Transmission electron micrographs (8000× magnification).

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