Fig. 2

Comparison of the two manual segmentation methods: (a) Manual Single Segmentation (MSS) applies a single mask to create the bone object, resulting in a surface layer of partial-volume voxels (red dots) at cortical bone boundaries that require careful handling during material assignment. According to Inglis et al.20, using a dual-zone material model corrects the partial volume artifacts in cortical bone. (b) Manual Dual Segmentation (MDS) is a multi-step reconstruction with two masks, resulting in a separation of cortical bone without partial-volume surface effects.