Table 4 Associations between Alzheimer’s disease (AD) genetic risk factors and AD or late-onset epilepsy (LOE), multi-task elastic net modeling sample (subset of UCLA ATLAS patient) (N = 9,986)a.

From: Multi-task learning identifies shared genetic risk for late-onset epilepsy and alzheimer’s disease

Outcome

N

APOE-ε4 count

AD PRS without APOE region

OR [95% CI]

P-value

OR [95% CI]

P-value

AD

9,986

2.85 (2.34, 3.48)

< 0.001*

1.15 (1.04, 1.27)

0.01*

LOE

9,986

1.20 (0.99, 1.45)

0.053

1.03 (0.95, 1.12)

0.52

  1. AD Alzheimer’s disease, CI confidence interval.
  2. [a]Basic Model adjustments include age at last visit, sex, and ancestry-specific principal components.
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