Table 5 Suggestively significant (p < 1 × 10− 5) SNPs from the GRC GOM cohort that reach nominal significance (p < 0.05) in the GOBS cohort and their associated cognitive measures.
Phenotype | Chrom. | SNP | GOM Effect Size (β) | GOM P-value | GOM MAF | Replication Test | Replication Effect Size (β) | Replication P-value | Replication MAF |
|---|---|---|---|---|---|---|---|---|---|
SVLT_LI | 12 | rs1032704 | 0.11 | 3.2 × 10− 6 | 0.452 | PCET Face Memory Test | 0.08 | 3.22 × 10− 2 | 0.456 |
SVLT_LI | 12 | rs4931672 | 0.11 | 2.5 × 10− 6 | 0.452 | PCET Face Memory Test | 0.08 | 2.74 × 10− 2 | 0.458 |
MIST_DELAY | 20 | rs6035340 | 2.33 | 7.93 × 10− 6 | 0.458 | CVLT Delay | 0.07 | 3.68 × 10− 2 | 0.460 |