Table 2 Hemodynamic parameters changes during heart IRI.

From: siRNA-mediated inhibition of NTT-MMP-2 reduces oxidative stress and apoptotic signaling in an ex vivo model of ischemia/reperfusion injury

Parameter

Groups

P-valued

Aero

I/R

I/R + siRNA

HR (bpm)a

276.5 ± 9.2

130.8 ± 26.6*

271.3 ± 13.7#

 < 0.001

LVDP (mm Hg)a

48.6 ± 3.5

22.8 ± 5.3*

52.6 ± 8.3#

 < 0.001

CF (mL/min)b

12.5 ± 0.6

8.0 ± 1.4*

12.8 ± 0.4#

0.04

Recovery of RPP (%)c

83.3 ± 4.4

39.9 ± 8.3*

96.4 ± 9.5#

 < 0.001

  1. Mean ± SEM;aAfter I/R (77th minute of the experiment);bAfter ischemia (47th minute – first minute of reperfusion);cDifference between RPP in 25th and 77th minutes of the experiment;dANOVA test;*p < 0.05 vs Aerobic;#p < 0.05 vs I/R. Significant values are in bold.
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