Table 4 Formulation of aripiprazole NLCs.
Formulation code | Factor 1 (lipid phase) | Factor 2 (aqueous phase) | Water % | ||||
|---|---|---|---|---|---|---|---|
Lipid phase [5–10%] | Liquid lipid [2.5-5%] | Solid lipid [2.5-5%] | Smix [20–50%] | Surfactant [13.33–33.33%] | Co-surfactant [6.66%-16.66%] | ||
A1 | 5.00 | 2.50 | 2.50 | 20.00 | 13.33 | 6.66 | 75.00 |
A2 | 7.50 | 3.75 | 3.75 | 20.00 | 13.33 | 6.66 | 72.50 |
A3 | 10.0 | 5.00 | 5.00 | 20.00 | 13.33 | 6.66 | 70.00 |
A4 | 5.00 | 2.50 | 2.50 | 50.00 | 33.33 | 16.66 | 45.00 |
A5 | 7.50 | 3.75 | 3.75 | 35.00 | 23.33 | 11.66 | 57.50 |
A6 | 10.0 | 5.00 | 5.00 | 35.00 | 23.33 | 11.66 | 55.00 |
A7 | 5.00 | 2.50 | 2.50 | 35.00 | 23.33 | 11.66 | 60.00 |
A8 | 7.50 | 3.75 | 3.75 | 50.00 | 33.33 | 16.66 | 42.50 |
A9 | 10.0 | 5.00 | 5.00 | 50.00 | 33.33 | 16.66 | 40.00 |
