Fig. 2
From: Identification of genetic variants associated with ear length in drop-eared dogs
Manhattan plots for ear carriage across 229 breeds. (A) GWAS results are shown for ear carriage, with insets depicting ear carriage phenotypes (left) and a Q-Q plot showing observed vs. expected -log10 P-values (right). Red line indicates Bonferroni significance (P = 8.78 × 10− 9). (B) Corresponding regional plot depicts pairwise LD (r2) with the lead SNV at chr10:8,386,190 (purple diamond). The SNVs used as covariates in panel C are represented as squares and indicated with arrows. (C) GWAS results for ear carriage using lead SNV for ear length and the allele for small body size as covariates, with inset Q-Q plot showing observed vs. expected -log10 P-values. Red line indicates Bonferroni significance (P = 8.78 × 10− 9). (D) Corresponding regional plot depicts pairwise LD (r2) with the lead SNV at chr10:8,397,522 (purple diamond).
