Table 1 Comparative overview between full factorial and reduced design.

From: Evaluating the efficiency of formaldehyde degradation from aqueous environment by sonozone technique

Design aspect

Full factorial (486)

Reduced design (15)

Objective

Exhaustive enumeration

Efficient inference with minimal runs

Estimable effects

All main, interactions, higher-order

Main + selected 2-way; higher-order assumed negligible

Orthogonality

High but costly

Maintained for primary effects

Alias/confounding

Minimal

Controlled; acceptable for higher-order terms

Power (primary outcomes)

Very high

Adequate for medium effects

Cost/time

Prohibitive

Feasible

Validation

Intrinsic via volume

External via confirmations and diagnostics