Fig. 1

(A) A schematic representation of the MEV construct, highlighting color-coded elements: the adjuvant (blue), CTL epitopes (green), HTL epitopes (red), B-cell epitopes (purple), and linkers (EAAAK, AAY, GPGPG, KK; shown in black). (B) The finalized MEV construct consists of 347 amino acids, including an adjuvant (grey) linked by an EAAAK linker (dark grey), CTL epitopes (cyan) joined by AAY linkers (blue), HTL epitopes (orange) connected through GPGPG linkers (red), and B-cell epitopes (green) linked using KK linkers (parrot).