Table 1 Phenotyping tests examined in this study.

From: Quantitative dissection of sexual dimorphism in mice through Y-linked gene knockouts and multivariate phenotyping

Test name

Abbreviation

Biological systems to be covered*

Data type

N of parameters

Acoustic startle and Pre-pulse Inhibition (PPI)

ACS

2, 6, 15

Quantitative

16

Clinical Blood Chemistry

CBC

8, 9

Quantitative

21

Combined SHIRPA and Dysmorphology

CSD

2, 4, 6, 7, 9, 11, 12, 14, 16, 18

Qualitative

83

Quantitative

6

Body Composition (DEXA lean/fat)

DXA

1, 6, 19

Quantitative

11

Electrocardiogram (ECG)

ECG

3

Quantitative

11

Eye Morphology

EYE

2, 3, 15, 16, 20

Qualitative

33

Grip Strength

GRS

2, 6

Quantitative

13

Hematology

HEM

8, 10

Quantitative

24

Immunophenotyping

IMM

6, 8, 10

Quantitative

65

Intraperitoneal glucose tolerance test (IPGTT)

IPG

6, 9

Quantitative

7

Open Field

OFD

2

Quantitative

15

Gross Pathology and Tissue Collection

PAT

3, 5, 6, 10, 13, 15, 17, 18

Quantitative

22

X-Ray

XRY

4, 12, 18, 19

Qualitative

59

Quantitative

1

Y-maze

YMZ

2

Quantitative

11

    

398

  1. *1:adipose tissue phenotype (MP:0005375), 2:behavior/neurological phenotype (MP:0005386), 3:cardiovascular system phenotype (MP:0005385), 4:craniofacial phenotype (MP:0005382), 5:endocrine/exocrine gland phenotype (MP:0005379), 6:growth/size/body region phenotype (MP:0005378), 7:hearing/vestibular/ear phenotype (MP:0005377), 8:hematopoietic system phenotype (MP:0005397), 9:homeostasis/metabolism phenotype (MP:0005376), 10:immune system phenotype (MP:0005387), 11:integument phenotype (MP:0010771), 12:limb/digit/tail phenotype (MP:0005371), 13:liver/biliary system phenotype (MP:0005370), 14:muscle phenotype (MP:0005369), 15:nervous system phenotype (MP:0003631), 16:pigmentation phenotype (MP:0001186), 17:renal/urinary system phenotype (MP:0005367), 18:reproductive system phenotype (MP:0005389), 19:skeleton phenotype (MP:0005390), 20:vision/eye phenotype (MP:0005391).