Fig. 2 | Scientific Reports

Fig. 2

From: HMBOX1 plays a critical role in plumbagin-induced growth inhibition of hepatocellular carcinoma cells

Fig. 2

HMBOX1 is shown as a target for PLB-mediated anti-tumor effects by CRISPR screening. (A) Experimental protocol in the high-throughput genetic screenings. (B) Scatter plot showing significant genes in positive selection analysis. (C) Schematic diagram shows targeting sgRNAs against HMBOX1 enriched in PLB-treated cells. (D,E) Box plots illustrating HMBOX1 expression profiles in TCGA hepatic tissues (D) and CPTAC liver cancer (E). Data were statistically analyzed by the ULCAN website.

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