Fig. 3 | Scientific Reports

Fig. 3

From: Advancing leprosy risk prediction through identification of a whole blood host transcriptomic biomarker signature including non-coding genes

Fig. 3

Differential gene expression (DGE) in whole blood samples between progressors and household contacts (HHC). mRNA levels were measured by RT-qPCR in whole blood RNA samples of progressors (n = 12) and HHC (n = 12). The Mann–Whitney U test was performed to determine the statistical significance between groups (adjusted p-values: * p < 0,05, ** p < 0,01, *** p < 0,001, **** p < 0,0001). Relative target gene expression was determined by calculating ∆Ct using GAPDH as a reference gene. Since mRNA levels were expressed as ΔCt values, larger values represent lower mRNA levels. ΔCt values were multiplied by −1.

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