Table 1 Baseline characteristics for glaucoma cases in 458,316 participants in UK Biobank.
From: Multimodal deep learning approaches for improving polygenic risk scores with imaging data
Covariates | Group | Glaucoma | ||
|---|---|---|---|---|
N (%) | #Case | Prev | ||
Age | All | 458,268 | 13,805 | 0.0301 |
<60 | 254,643 (55.57) | 4,099 | 0.0161 | |
>=60 | 203,625 (44.43) | 9,706 | 0.0477 | |
P-value | Â | < 2.20*10-16 | ||
Sex | All | 458,268 | 13,805 | 0.0301 |
Female | 248,673 (54.26) | 6,719 | 0.0270 | |
Male | 209,595 (45.74) | 7,086 | 0.0338 | |
P-value | Â | 7.93*10-7 | ||
Alcohol | All | 458,268 | 13,805 | 0.0301 |
Prefer not to answer | 328 (0.07) | 13 | 0.0396 | |
Daily or almost daily | 96,569 (21.07) | 3,252 | 0.0337 | |
Three or four times a week | 109,354 (23.86) | 3,133 | 0.0287 | |
Once or twice a week | 120,487 (26.29) | 3,231 | 0.0268 | |
One to three times a month | 51,125 (11.16) | 1,413 | 0.0276 | |
Special occasions only | 49,531 (10.81) | 1,646 | 0.0332 | |
Never | 30,874 (6.74) | 1,117 | 0.0362 | |
P-value | Â | 6.06*10-11 | ||
Smoke | All | 458,268 | 13,805 | 0.0301 |
Prefer not to answer | 1,634 (0.36) | 58 | 0.0355 | |
Never | 246,338 (53.75) | 7,018 | 0.0285 | |
Previous | 162,505 (35.46) | 5,489 | 0.0338 | |
Current | 47,791 (10.43) | 1,240 | 0.0259 | |
P-value | Â | 3.76*10-12 | ||
Health | All | 458,267 | 13,805 | 0.0301 |
Prefer not to answer | 113 (0.02) | 6 | 0.0531 | |
Do not know | 1,648 (0.36) | 56 | 0.0340 | |
Excellent | 76,727 (16.74) | 1,777 | 0.0232 | |
Good | 266,389 (58.13) | 7,645 | 0.0287 | |
Fair | 93,788 (20.47) | 3,428 | 0.0366 | |
Poor | 19,602 (4.28) | 893 | 0.0456 | |
P-value | Â | 3.44*10-13 | ||
Illness | All | 458,267 | 13,805 | 0.0301 |
Prefer not to answer | 668 (0.15) | 34 | 0.0509 | |
Do not know | 9,965 (2.17) | 351 | 0.0352 | |
No | 302,067 (65.92) | 7,079 | 0.0234 | |
Yes | 145,567 (31.76) | 6,341 | 0.0436 | |
P-value | Â | < 2.20*10-16 | ||
Townsend | All | 457,728 | 13,791 | 0.0301 |
Q1 | 114,506 (25.02) | 3,513 | 0.0307 | |
Q2 | 114,373 (24.99) | 3,438 | 0.0301 | |
Q3 | 114,434 (25.00) | 3,309 | 0.0289 | |
Q4 | 114,415 (25.00) | 3,531 | 0.0309 | |
P-value | Â | 1.31*10-2 | ||
Education | All | 457,842 | 13,779 | 0.0300 |
None of the above | 79,021 (17.26) | 3,110 | 0.0394 | |
Prefer not to answer | 4,069 (0.89) | 166 | 0.0408 | |
College or University degree | 146,571 (32.01) | 3,971 | 0.0271 | |
A levels/AS levels or equivalent | 51,637 (11.28) | 1,347 | 0.0261 | |
O levels/GCSEs or equivalent | 98,376 (21.49) | 2,921 | 0.0297 | |
CSEs or equivalent | 24,668 (5.39) | 472 | 0.0191 | |
NVQ or HND or HNC or equivalent | 30,002 (6.55) | 946 | 0.0315 | |
Other professional qualifications | 23,498 (5.13) | 846 | 0.0360 | |
P-value | Â | < 2.20*10-16 | ||
Ethnic | All | 458,268 | 13,805 | 0.0301 |
1 | 542 (0.12) | 16 | 0.0295 | |
1001 | 429,308 (93.68) | 12,995 | 0.0303 | |
1002 | 12,689 (2.77) | 379 | 0.0299 | |
1003 | 15,729 (3.43) | 415 | 0.0264 | |
P-value | Â | 6.66*10-2 | ||
Country birth | All | 458,316 | 13,805 | 0.0301 |
Prefer not to answer | 147 (0.03) | 4 | 0.0272 | |
England | 371,802 (81.13) | 11,540 | 0.0310 | |
Wales | 21,311 (4.65) | 579 | 0.0272 | |
Scotland | 38,847 (8.48) | 932 | 0.0240 | |
Northern Ireland | 2,951 (0.64) | 105 | 0.0356 | |
Republic of Ireland | 4,717 (1.03) | 164 | 0.0348 | |
Elsewhere | 18,493 (4.04) | 481 | 0.0260 | |
P-value | Â | < 2.20*10-16 | ||
