Table 6 \(\:{Q}_{inhib}^{\left(\alpha\:\right)}\) For each system and enzyme Inhibition \(\:{IC}_{50}\) For each compound.

From: Affinity of drug candidates binding to SARS-CoV-2 PLpro assessed using a generalized-ensemble method

System (\(\:\alpha\:\))

\(\:{Q}_{inhib}^{\left(\alpha\:\right)}\)

IC50 (ÎĽM)

Set 1

Set 2

Set 3

PLpro-GRL0617

0.349

0.311

0.536

1.61

PLpro-XR8-24

0.303

0.215

0.335

0.56

PLpro-XR8-23

0.233

0.171

0.282

0.39

PLpro-ZN-3-56

0.19

0.113

0.200

3.9

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