Fig. 6 | Scientific Reports

Fig. 6

From: Single-cell transcriptomics and spatial validation reveal dysfunction of keratinocytes and NK cells driving acne development

Fig. 6

Functional enrichment and cell-cell communication analysis reveal dynamic remodeling of NK cell-keratinocyte interactions during acne progression. (A) String diagram of cell-cell communication between NK cell and keratinocyte subpopulations in mild acne lesions. (B) String diagram of cell-cell communication between NK cells and keratinocyte subpopulations in severe acne lesions. (C–D) Pathway enrichment analysis of N0 (C) and N8 (D) (MA vs. NC). (E–H) Pathway enrichment analysis of KC2(E), KC3(F), KC4(G), and KC14 (H) (MA vs. NC). The figure is from the KEGG database (www.kegg.jp/kegg/kegg1.html) [Map ID: e.g., hsa00190] and is used with permission from Kanehisa Laboratories.

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