Table 3 Univariate and multivariate analyses of risk factors for POD24 in DLBC - PCNSL.
Univariate | Multivariate | |||
|---|---|---|---|---|
Factors | OR (95%CI) | P value | OR (95%CI) | P value |
Age | 1.13 (0.44–2.91) | 0.80 | ||
Gender, female | 0.62 (0.26–1.49) | 0.29 | ||
β2M > 2.7 µg/mL | 6.00 (0.70–51.58) | 0.103 | ||
D-Dimer > 2 mg/L | 1.05 (0.39–2.85) | 0.92 | ||
KPS scores | 0.97 (0.94–1.00) | 0.05 | ||
MSKCC | 0.96 (0.52–1.79) | 0.90 | ||
GCB subtype | 2.35 (0.79–7.05) | 0.13 | ||
Ki 67 ≥ 80% | 0.72 (0.29–1.81) | 0.49 | ||
ECOG score > 2 | 2.58 (0.66–10.20) | 0.18 | ||
LDH > 225 u/L | 5.05 (1.05–24.26) | 0.04 | 12.00 (1.27–113.58) | 0.03 |
TG > 1.7 mmol/L | 3.89 (1.14–13.29) | 0.03 | 4.88 (1.02–23.33) | 0.047 |
CHOL > 5.2 mmol/L | 1.11 (0.37–3.33) | 0.86 | ||
CREA | 0.99 (0.97–1.02) | 0.59 | ||
Elevated protein levels in CSF | 0.75 (0.17–3.31) | 0.71 | ||
Albumin < 40 g/L | 1.04 (0.43–2.49) | 0.93 | ||
HbsAg positive | 3.05 (0.61–15.34) | 0.18 | ||
WBRT | 1.23 (0.27–5.54) | 0.79 | ||
Excision of intracranial tumor | 0.16 (0.03–0.76) | 0.02 | ||
Residual parenchymal central system lymphoma | 4.05 (1.51–10.86) | 0.005 | ||
Regimens without RTX | 1.91 (0.71–5.14) | 0.20 | ||
ASCT | 0.83 (0.21–3.36) | 0.80 | ||
Non-responsive diseases | 6.36 (1.90–21.34) | 0.003 | 9.39 (2.16–40.87) | 0.003 |
