Fig. 1 | Scientific Reports

Fig. 1

From: Enhancing MRI contrast between sub-chronic myocardial infarct, remote and healthy myocardium using periodic irradiation in the rotating frames

Fig. 1

A schematic diagram of the ischemia-reperfusion injury, which is causing fibronectin (Fn1) to upregulate. This is causing the inhibition of liver-kinase B1 AMP-activated protein kinase (LKB1-AMPK) signaling, which is further promoting nuclear factor kappa-light-chain-enhancer of activated B cells (NF-KB) and transforming growth factor beta 1 (TGF-B1) signaling pathways leading to cardiomyocyte apoptosis, fibrosis and inflammation. The figure is modified from2.

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