Table 1 One-pot three-component CuAAC reaction by different conditions.

From: Lead free perovskite integrated metal organic framework as heterogeneous catalyst for efficient three component click reaction

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Entry

Solvent

Temperature

Time (min)

Yield (%)a

1

H2O

r.t.

45

90, 87b, 86c, 86,d 85e

2

H2O

50

40

90

3

EtOAc

r.t.

360

90

4

EtOH

r.t.

45

86

5

CH3CN

r.t.

480

50

6

H2O + EtOH

r.t.

45

89

7f

H2O

r.t.

45

–

8g

H2O

r.t.

45

80

9h

H2O

r.t.

60

46

10i

H2O

r.t.

60

–

11j

H2O

r.t.

60

–

  1. Reaction conditions: I (0.5 mmol), II (1 mmol), III (1 mmol), solvent (2 mL), and CsCu2I3@UiO-66(Ce)-NH2 composite as catalyst (10 mg).
  2. aPurified yield.
  3. bThe second reused.
  4. cThe third reused.
  5. dThe forth reused.
  6. eThe fifth reused.
  7. fPristine UiO-66-NH2 as catalyst.
  8. gIndividual CsCu2I3 as catalyst.
  9. hCuI as catalyst.
  10. iBDC-NH2 as catalyst.
  11. j(NH4)Ce(NO3)6 as catalyst.
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