Fig. 1
From: GNG2 inhibits brain metastases from colorectal cancer via PI3K/AKT/mTOR signaling pathway
High GNG2 expression is associated with better prognosis in CRC. (A) The Protein–Protein interaction (PPI) network map of differentially expressed genes (DEGs) between metastatic tumor tissue and normal tissue. Node size was proportional to its degree. Red nodes represented upregulated genes, and blue nodes represent downregulated genes. (B) The sequence of the top 30 genes with the highest degrees. (C) GNG2 expression levels were obtained from the TCGA database between metastatic tumor tissue and the normal tissue. (D) The pairing difference analysis of GNG2 expression between metastatic tumor tissue and normal tissue. (E) Kaplan-Meier survival for predicting GNG2 expression related overall survival (p = 0.015) using TCGA database. (F) GNG2 expression profiles in multiple cancers using TCGA database.
