Fig. 4
From: Molecular mechanism of type ib MET inhibitors and their potential for CNS tumors

Interaction strength between drugs and residue Y1230 and its influencing factors. (A) Decomposed binding energy of Y1230, calculated by MM/GBSA. (B) The dihedral angle distribution of the rotatable bond significantly influences interaction with Y1230, where the four constituent atoms are depicted as spherical entities.