Table 1 Permeability results of test compounds in MDCK-MDR1 cell line.

From: Molecular mechanism of type ib MET inhibitors and their potential for CNS tumors

Compound

Papp (cm/s × 10− 6)

Efflux ratio

A to B

B to A

Vebreltinib

21.16

25.95

1.23

Glumetinib

12.97

18.03

1.39

Capmatinib

24.06

26.72

1.11

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