Table 1 Numbers and ASRs per 100,000 cases of prevalence of esophageal cancer in 1990 and 2019, along with the ralative changes and AAPC in ASRs per 100,000 cases from 1990–2019, categorized by global, SID and GBD regions.
Characteristic | Number in 1990 (95% CI) | Age-standardized Rate in 1990 (95% CI) | Number in 2019 (95% CI) | Age-standardized rate in 2019 (95% CI) | Relative change of numbers from 1990 to 2019(%) | Relative change of age-standardized rate from 1990 to 2019(%) | AAPC (Age-standardized rate, 95% CI) | P value |
|---|---|---|---|---|---|---|---|---|
Global | 489,194 (388,238 to 536,586) | 12 (9.6 to 13.1) | 960,610 (840,399 to 1,068,485) | 11.6 (10.1 to 12.9) | 96.37 | -3.58 | -0.14 (-0.24 to -0.04) | 0.005 |
High SDI | 96,681 (93,981 to 98,748) | 9.5 (9.3 to 9.8) | 219,163 (197,989 to 241,176) | 12.3 (11.1 to 13.6) | 126.69 | 29.03 | 0.84 (0.74 to 0.94) | < 0.001 |
High-middle SDI | 127,273 (106,634 to 140,142) | 11.6 (9.7 to 12.8) | 255,801 (195,116 to 300,313) | 12.4 (9.5 to 14.5) | 100.99 | 7.1 | 0.23 (0.13 to 0.33) | < 0.001 |
Middle SDI | 200,314 (118,186 to 232,065) | 18.7 (11.1 to 21.7) | 355,071 (282,700 to 414,306) | 14 (11.1 to 16.3) | 77.26 | -25.38 | -1.04 (-1.17 to -0.9) | < 0.001 |
Low-middle SDI | 44,174 (38,923 to 56,965) | 6.9 (6.1 to 8.9) | 89,058 (78,281 to 124,219) | 6.2 (5.5 to 8.8) | 101.61 | -9.31 | -0.33 (-0.46 to -0.2) | < 0.001 |
Low SDI | 20,636 (17,041 to 23,835) | 8.1 (6.7 to 9.2) | 41,265 (33,963 to 49,382) | 7.4 (6.1 to 8.8) | 99.97 | -7.97 | -0.29 (-0.35 to -0.22) | < 0.001 |
Andean Latin America | 528 (446 to 599) | 2.5 (2.2 to 2.9) | 1,140 (912 to 1,427) | 2 (1.6 to 2.5) | 115.74 | -20.01 | -0.75 (-1.19 to -0.31) | 0.001 |
Australasia | 1,827 (1,726 to 1,921) | 7.8 (7.4 to 8.2) | 4,006 (3,232 to 4,968) | 8.3 (6.7 to 10.4) | 119.23 | 6.91 | 0.23 (-0.04 to 0.5) | 0.095 |
Caribbean | 1,399 (1,312 to 1,507) | 5.4 (5 to 5.8) | 2,961 (2,517 to 3,426) | 5.7 (4.8 to 6.6) | 111.7 | 6.06 | 0.33 (0.19 to 0.47) | < 0.001 |
Central Asia | 9,088 (8,798 to 9,427) | 18.8 (18.2 to 19.6) | 7,010 (6,186 to 8,290) | 9 (8 to 10.6) | -22.87 | -52.02 | -2.51 (-2.76 to -2.26) | < 0.001 |
Central Europe | 6,274 (6,122 to 6,430) | 4.2 (4.1 to 4.3) | 8,957 (7,763 to 10,243) | 4.6 (3.9 to 5.2) | 42.77 | 8.21 | 0.17 (0 to 0.33) | 0.044 |
Central Latin America | 2,671 (2,588 to 2,743) | 3.2 (3.1 to 3.3) | 5,634 (4,767 to 6,583) | 2.4 (2 to 2.8) | 110.93 | -25.08 | -1.03 (-1.33 to -0.72) | < 0.001 |
Central Sub-Saharan Africa | 3,564 (1,631 to 4,761) | 14.3 (6.6 to 19) | 6,470 (3,453 to 8,786) | 11.2 (6 to 15.3) | 81.53 | -21.47 | -0.84 (-0.97 to -0.7) | < 0.001 |
East Asia | 258,241 (164,354 to 303,318) | 28.3 (18.2 to 33.1) | 511,950 (394,879 to 608,640) | 23.9 (18.3 to 28.3) | 98.25 | -15.57 | -0.59 (-0.74 to -0.44) | < 0.001 |
Eastern Europe | 18,127 (17,431 to 19,232) | 6.3 (6.1 to 6.7) | 17,805 (15,466 to 20,314) | 5.3 (4.6 to 6.1) | -1.77 | -15.97 | -0.56 (-1.45 to 0.33) | 0.215 |
Eastern Sub-Saharan Africa | 12,070 (9,071 to 14,199) | 14.9 (11.3 to 17.5) | 24,095 (18,215 to 30,635) | 13.7 (10.4 to 17.4) | 99.63 | -8.01 | -0.3 (-0.49 to -0.11) | 0.002 |
High-income Asia Pacific | 32,110 (30,719 to 33,522) | 15.6 (14.9 to 16.2) | 78,954 (66,451 to 93,361) | 19.1 (16 to 22.6) | 145.88 | 22.45 | 0.61 (0.36 to 0.86) | < 0.001 |
High-income North America | 22,093 (21,483 to 22,664) | 6.6 (6.4 to 6.8) | 46,983 (40,331 to 54,880) | 7.8 (6.7 to 9.1) | 112.66 | 17.68 | 0.52 (0.38 to 0.66) | < 0.001 |
North Africa and Middle East | 6,446 (4,389 to 7,728) | 3.5 (2.5 to 4.2) | 15,729 (11,584 to 18,012) | 3.5 (2.6 to 3.9) | 144.02 | -1.54 | -0.05 (-0.16 to 0.06) | 0.345 |
Oceania | 91 (68 to 127) | 2.8 (2.2 to 4) | 216 (161 to 289) | 2.8 (2.1 to 3.8) | 136.89 | -0.07 | -0.02 (-0.06 to 0.02) | 0.286 |
South Asia | 37,657 (33,048 to 47,049) | 6.1 (5.4 to 7.6) | 79,148 (68,370 to 105,673) | 5.3 (4.6 to 7.2) | 110.18 | -12.48 | -0.41 (-0.6 to -0.22) | < 0.001 |
Southeast Asia | 10,483 (8,903 to 11,904) | 3.8 (3.3 to 4.3) | 24,639 (20,694 to 28,965) | 3.8 (3.2 to 4.5) | 135.04 | 0.25 | 0 (-0.14 to 0.15) | 0.979 |
Southern Latin America | 4,660 (4,506 to 4,802) | 10.1 (9.7 to 10.4) | 5,751 (4,555 to 7,276) | 7 (5.5 to 8.8) | 23.41 | -30.87 | -1.32 (-1.57 to -1.07) | < 0.001 |
Southern Sub-Saharan Africa | 5,514 (4,122 to 6,777) | 18.8 (14 to 23.2) | 8,570 (7,624 to 10,186) | 14.6 (13 to 17.1) | 55.43 | -22.38 | -0.88 (-1.57 to -0.18) | 0.014 |
Tropical Latin America | 9,071 (8,747 to 9,431) | 9.4 (9 to 9.8) | 19,366 (18,364 to 20,289) | 7.8 (7.4 to 8.1) | 113.48 | -17.23 | -0.65 (-0.8 to -0.49) | < 0.001 |
Western Europe | 44,691 (43,644 to 45,585) | 8.3 (8.1 to 8.4) | 84,093 (73,119 to 96,578) | 10.4 (9 to 12) | 88.17 | 25.35 | 0.78 (0.58 to 0.99) | < 0.001 |
Western Sub-Saharan Africa | 2,588 (2,217 to 3,026) | 2.8 (2.4 to 3.3) | 7,133 (5,425 to 8,651) | 3.6 (2.7 to 4.3) | 175.59 | 28.62 | 0.89 (0.82 to 0.96) | < 0.001 |
