Fig. 6
From: Assessment of Hsp90β-selective inhibitor safety and on-target effects
A hERG fluorescence polarization assay was performed in a 1:3 serial dilution in quadruplicate wells. The top was constrained to the untreated (tracer fully bound) negative control wells and the bottom to the 30 µM E-4031 (fully displaced) positive control wells represented as dashed lines. Polarization values are reported as the Avg ± SD with N = 4 technical replicates.
