Table 1 Demographic data, and clinical characteristics.

From: Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery

 

A (n = 39; 34.2%)

B (n = 37; 32.5%)

C (n = 38; 33.3%)

A vs C

P*

B vs C

P*

A vs B

P*

Age

56.5 ± 9.4

57.2 ± 10.2

54.8 ± 11.2

0.47

0.34

0.79

Palpable mass

6 (15.4)

7 (18.9)

6 (15.8)

1

0.77

0.78

ASA

      

 1–2

34 (87.2)

34 (91.9)

30 (78.9)

0.37

0.19

0.71

 3–4

5 (12.8)

3 (8.1)

8 (21.1)

0.38

0.19

0.71

BMI

      

 < 30

24 (61.5)

20 (54.1)

19 (50)

0.36

0.82

0.64

 ≥ 30

15 (38.5)

17 (45.9)

19 (50)

0.36

0.82

0.64

Previous breast surgery

1 (2.6)

1 (2.7)

2 (5.3)

0.61

1

1

Cardiological disease

12 (30.8)

15 (40.5)

14 (37.8)

0.63

0.81

0.48

Pulmonary disease

1 (2.6)

2 (5.4)

0 (0)

1

0.24

0.61

Renal disease

0 (0)

0 (0)

1 (2.6)

0.49

1

1

Hepatic disease

0 (0)

0 (0)

1 (2.6)

0.49

1

1

Other types of cancer

2 (5.1)

0 (0)

2 (5.4)

1

0.22

0.49

Anticoagulant/antiplatelet drugs

3 (7.7)

4 (10.8)

1 (2.7)

0.61

0.2

0.71

Corticosteroids/immunosuppressant drugs

2 (5.1)

0 (0)

1 (2.7)

1

1

0.49

NAC

1 (0.9)

0 (0)

0 (0)

1

1

1

Previous neck/chest radiotherapy

0 (0)

0 (0)

1 (2.6)

0.49

1

1

  1. Data shown as average ± standard deviation or as absolute frequency with percentage in brackets. *Student’s t test for independent samples for continuous values or χ2/Fisher’s exact test for ordinal/binomial variables.
  2. Group A CBB + neurotrophic agents administration, Group B CBB + placebo administration, Group C double placebo administration.
  3. ASA American Society of Anesthesiologists, BMI body mass index, NAC neoadjuvant chemotherapy.