Table 2 Perioperative data, type of surgery, and histology.

From: Randomized controlled trial of bromelain and alpha-lipoic acid in breast conservative surgery

Perioperative data, N (%)

A (n = 39; 34.2%)

B (n = 37; 32.5%)

C (n = 38; 33.3%)

A vs C

P*

B vs C

P*

A vs B

P*

Quadrantectomy

3 (7.7)

5 (13.5)

2 (5.3)

1

0.26

0.47

Quadrantectomy + SLNB

35 (89.7)

28 (75.7)

32 (84.2)

0.52

0.40

0.13

Quadrantectomy + ALND

/

2 (5.4)

3 (7.9)

0.12

1

0.23

Quadrantectomy + SLNB + ALND

1 (2.6)

2 (5.4)

1 (2.6)

1

0.61

0.61

Operative time (min)

115 ± 29

118 ± 26

124 ± 35

0.15

0.28

0.65

Hospital stay (hours)

30 ± 11

34 ± 12

35 ± 14

0.23

0.84

0.27

 DCIS

14 (35.9)

12 (32.4)

13 (34.2)

1

1

0.81

 IDC

21 (53.8)

22 (59.5)

21 (55.3)

1

0.82

0.65

 ILC

4 (10.3)

3 (8.1)

4 (10.5)

1

1

1

Luminal A

12 (30.8)

20 (54.1)

10 (26.3)

0.80

0.21

0.06

Luminal B

9 (30.7)

6 (16.2)

13 (34.2)

0.32

0.11

0.57

HER2-enriched

/

/

1 (2.6)

0.49

1

1

Basal like

1 (2.6)

2 (5.4)

1 (2.6)

1

0.61

0.61

  1. Data shown as average ± standard deviation or as absolute frequency with percentage in brackets.
  2. Group A CBB + neurotrophic agents administration, Group B CBB + placebo administration, Group C double placebo administration.
  3. SLNB sentinel lymph-node biopsy, ALND axillary lymph-node dissection, DCIS ductal carcinoma in situ, IDC infiltrative ductal carcinoma, ILC infiltrative lobular carcinoma.