Fig. 13 | Scientific Reports

Fig. 13

From: Immunoinformatics based designing of a multi-epitope cancer vaccine targeting programmed cell death ligand 1

Fig. 13The alternative text for this image may have been generated using AI.

The in-silico simulation of the immune response to the designed vaccine construct, as predicted by the C-ImmSim (https://kraken.iac.rm.cnr.it/C-IMMSIM/index.php) server. (A) The production of IgG1 + IgG2 and IgM indicates the advancement of secondary and tertiary immune responses, (B) The B-cell population following three injections, (C) Shows elevated levels in the populations of active T-cytotoxic cells and (D) T-helper cells per state following the injections, respectively, (E) Production of cytokines and interleukins along with the Simpson Index as a measure of the immune response.

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