Table 4 Comparison of Clinicopathological and Imaging characteristics of malignant papillary lesions with PND or not.

From: Analysis of the clinicopathological and imaging features in breast intraductal papillary lesions with or without pathological nipple discharge

Variable

PND group (n=28)

non-PND group (n=27)

X2

P-value

Age (year)

 ≤50

12

2

9.103

0.003

 >50

16

25

Lesion size

 ≤1 cm

22

7

15.284

<0.001

 >1 cm

6

20

Palpatable mass

 Yes

4

23

27.647

<0.001

 No

24

4

Distance of lesion from nipple

 ≤2 cm

18

14

0.873

0.35

 >2 cm

10

13

Vascularity on US

 Yes

17

17

0.029

0.864

 No

11

10

Abnormal galactography or mammogram

 Yes

21

21

0.059

0.808

 No

7

6

DCIS (including SPC, EPC)

25

16

6.531

0.011

 IDC

3

11

ER/PR expression

 Positive

18

25

6.457

0.011

 Negative

10

2

Her-2 expresion

 +++

8

1

6.211

0.013

 -~++

20

26

Ki67 expresion

 <15%

21

14

3.184

0.074

 ≥15%

7

13

  1. DCIS: Ductal carcinoma in situ; SPC: Solid papillary carcinoma; EPC: Encapsulated papillary carcinoma; IDC: Invasive ductal carcinoma; ER: Estrogen receptor; PR: Progestin reseptor, Her-2: Human epidermal growth factor receptor-2; Ki67: Nuclear proliferation-associated antigen.
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