Fig. 5 | Scientific Reports

Fig. 5

From: The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions

Fig. 5

mRNA expression of inflammation-related genes in NCM460 and HCT116 cells infected with adenovirus expressing SERPINB4 or its mutant, followed by TNFA stimulation. (A, B) Relative mRNA expression of IL1B and IL24 in NCM460 cells. (C–F) Relative mRNA expression of IL6, IL17, CCL2, and CXCR2 in HCT116 cells. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 (One-way ANOVA with Tukey’s multiple comparisons test).

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