Table 2 Description of the new variants found in the indigenous population of the Amazon, found in the MLH1 and MSH6 genes.

From: Identification of genomic variants associated with colorectal cancer heredity in indigenous populations of the Amazon

Gene

Chrom*

Position

Change in nucleotide

Impact predicted by SnpEff

Alteration

Freq.INDG

MLH1

chr3

37,028,756

G > T

Modifier

Intron

0,025

MLH1

chr3

37,011,883

G > A

Modifier

Intron

0,034

MSH6

chr2

47,806,751

CT > C

Modifier

Intron

0,444

  1. INDG Amazonian indigenous population.
  2. (*) Reference genome to chromosomal location obtained from CH38 of the human genome of the Human Genome Project; Variant position; Change in nucleotide; Impact predicted by SnpEff; Alteration Type.
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