Table 5 Sensitivity analysis on the association of cholecystectomy with risk of depression among male or female.

From: Association of cholecystectomy with short-term and long-term risks of depression and suicide

 

No Cholecystectomy

Cholecystectomy

Male

40,410

4,041

Events, n

2,213

327

Per 1,000 person-y

321.795

31.028

aHR (95% CI)

1.00 (Ref.)

1.17 (1.03-1.33)*

Short-term risk (≤3 years)

38,928

3,872

Events, n

731

158

Per 1,000 person-y

311.378

29.823

aHR (95% CI)

1.00 (Ref.)

1.37 (1.11-1.67)**

Long-term risk (>3 years)

39,679

3,883

Events, n

1,482

169

Per 1,000 person-y

320.687

31.057

aHR (95% CI)

1.00 (Ref.)

1.07 (0.91-1.26)

Female

26,470

2,647

Events, n

2,447

360

Person-years

225.427

21.270

aHR (95% CI)

1.00 (Ref.)

1.19 (1.06-1.35)**

Short-term risk (≤3 years)

24,763

2,459

Events, n

740

172

Per 1,000 person-y

213.389

20.020

aHR (95% CI)

1.00 (Ref.)

1.39 (1.13-1.70)**

Long-term risk (>3 years)

25,730

2,475

Events, n

1,707

188

Per 1,000 person-y

224.302

21.362

aHR (95% CI)

1.00 (Ref.)

1.10 (0.95-1.29)

  1. Acronyms: aHR, adjusted hazard ratio; CI, confidence interval.
  2. The aHR adjusted for age, sex, household income, smoking status, alcohol consumption, physical activity, body mass index, systolic blood pressure, diastolic blood pressure, fasting serum glucose, total cholesterol, and Charlson comorbidity index.
  3. *p<0.05, **p<0.01.