Fig. 8 | Scientific Reports

Fig. 8

From: Improvement of carboplatin chemosensitivity in lung cancer cells by siRNA-mediated downregulation of DLGAP1-AS2 expression

Fig. 8

Effect of combination therapy on migration of A549 cells. (A) Downregulation of lncRNA-DLGAP1-AS2 expression and treatment with carboplatin can reduce A549 cell migration. (B) A graph illustrating the open wound area after 72 h. The results are expressed as the mean of three independent runs. (C) qRT-PCR results showed a significant reduction in MMP-2 and MMP-9 mRNA expression in the treatment groups, especially in the combination group (****P < 0.0001, ***P < 0.001, **P < 0.01).

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